The Hemoglobin A1C Test: Uses, Procedure, And Target Levels

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Everything you need to know about the A1C test

Medically reviewed by Angelica Balingit, MD — Written by Markus MacGill and Zia Sherrell, MPH — Updated on February 14, 2023

What is it?
What to expect
Who should get one?
A1C results explained
What can affect results?
eAG
Targets
A1C and self-monitoring
Importance of testing
Pregnancy
Test frequency
Outlook
Summary

The A1C test — also called the hemoglobin A1C or HbA1c test — is a simple blood test that measures a person’s average blood sugar level over the previous 3 months. It can help diagnose and monitor diabetes.

In a blood glucose test, a person checks how much sugar — or glucose — is in their blood. They can do this at home with a fingerprick test or through a wearable monitor.

A person can also visit a doctor’s office for an A1C test. This provides an average view of blood sugar levels over an extended period of time, usually 2–3 months. A1C testing is essential for most people with diabetes.

Read more to learn about how the test works, what it measures, and more.

What is the A1C test?

A young woman reads her test results. — MesquitaFMS/Getty Images

The A1C test is a blood test that measures the average glucose levels in the blood over the previous 3 months.

Doctors use the A1C test to determine how stable a person’s blood sugar levels are. They can also use it in the initial diagnosis of type 2 diabetes.

Other names for the A1C test include:

the hemoglobin A1C test
the glycated hemoglobin test
the glycohemoglobin test
the HbA1C test stands for

The HbA1C test stands for hemoglobin A1c. Hemoglobin is the protein in red blood cells that transports oxygen around the body.

Glucose attaches to hemoglobin to form glycated hemoglobin, which is also called hemoglobin A1C. When blood sugar levels are high, the body creates more glycated hemoglobin.

The A1C test measures these levels. Red blood cells live for around 120 days, or 4 months, and the A1C test measures the average blood glucose level over their lifespan.

What to expect

A person can take the A1C test at any time. They do not need to fast before taking it or do any other preparation.

To perform the test, a doctor or other healthcare professional will draw blood either from a finger stick or a bvein in the arm. They then send it to a laboratory for testing.

Some doctors’ offices offer a point-of-care test, which means they analyze the blood themselves. While this may be useful for managing diabetes, the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDKD) says that it is not suitable for diagnosis.

Who should get an A1C test?

The A1C test is one of the tests doctors use to diagnose type 2 diabetes and prediabetes. They may also use other tests, such as a fasting blood glucose test or a 2-hour glucose tolerance test.

For adults over 45 years or for people with certain risk factors, doctors repeat the A1C test every 3 years.

If the A1C test shows someone has prediabetes, they can make lifestyle changes to lower their risk for type 2 diabetes. A doctor may advise repeating the A1C yearly or every 2 years.

Additionally, people living with diabetes typically have their A1C levels monitored regularly. This can help them manage their medications and health.

Learn more about preventing type 2 diabetes.

A1C results explained

A1C test results show as a percentage. They refer to the amount of hemoglobin that glucose has bound to in a person’s blood.

For diagnosis, the test results may be as follows:

Normal: Below 5.7%
Prediabetes: 5.7–6.4%
Diabetes: 6.5% or more

One A1C test result does not mean that a person has diabetes. According to the NIDDK, if the A1C test shows 6.8%, the actual reading could be anywhere between 6.4–7.2%.

If the results show elevated A1C, a doctor may also check the person’s current blood sugar levels. If they are 200 milligrams per deciliter (mg/dl) or over, the doctor may diagnose diabetes.

A doctor will repeat these tests if A1C results, glucose scores, or both suggest a person has diabetes.

Additionally, a doctor may diagnose prediabetes if the results are 5.7–6.4%.

A person with prediabetes has a higher chance of developing type 2 diabetes in the future, but lifestyle changes, such as quitting smoking, following a healthy diet, and taking regular exercise, can often reduce the risk.

The person may already have risk factors for type 2 diabetes, such as:

obesity
high blood pressure
high cholesterol or triglycerides in the blood plasma
low levels of high-density lipoproteins (HDL)

The A1C test is useful for diagnosis, but it is also important for diabetes monitoring. Regular A1C and glucose testing can show a doctor if a person’s treatment is working or needs adjustment.

What can affect A1C results?

Certain factors can cause inaccurate A1C results, including:

kidney problems
liver disease
severe anemia
blood loss or blood transfusions
early or late pregnancy
medications, such as opioids and some HIV medications
low iron levels
being unwell
stress

Furthermore, certain people may have a less common type of hemoglobin that can affect the test results. This includes individuals of African, Mediterranean, or Southeast Asian descent, as well as people with blood disorders such as sickle cell anemia or thalassemia.

If these factors apply, a doctor may suggest alternative or additional tests.

What is eAG?

Average glucose, or eAG, is another way of reporting the results from an A1C test. It means the same thing, but some people prefer this way of interpreting the results because it uses the unit mg/dl — the same as the self-monitoring blood glucose test.

The eAG score gives an idea of the average glucose levels in a person’s blood over the previous 2–3 months, but it does not show the highs and lows that continuous glucose monitoring or the regular fingerprick test can reveal.

Here is a comparison between the two scores based on a calculator from the American Diabetes Association (ADA).

A1C (%)	eAG (mg/dl)
5.7	117
6.4	137
6.5	140
7	154
8	183
9	212
10	240

Target levels

The ideal A1C level for a person can be a moving target. It can vary depending on a person’s age, medical conditions, and more.

A doctor can make recommendations based on these factors. They will also track changes in a person’s A1C levels over time.

A1C and self-monitoring

Individuals living with diabetes have a customized treatment plan. An essential part of this plan involves a person self-monitoring their diabetes at home using a blood glucose meter or another device.

A person’s diabetes care team tells them how regularly and when they should test their blood sugar.

The self-monitoring device typically reports blood sugar levels in mg/dl. This measurement is a snapshot of blood glucose levels at the time of the test. Therefore, the levels vary depending on what a person eats, how much physical activity they do, and other factors, such as stress.

Self-monitoring helps people manage their diabetes and allows them to track whether they are meeting their A1C target.

Why is testing important?

It is important for people to manage blood sugar and A1C levels because experts associate increased levels with health complications, even if a person does not have diabetes. Elevated A1C levels are a significant risk factor for cardiovascular diseases and stroke in people who may have diabetes.

As A1C percentages rise, so does the risk of prediabetes becoming type 2 diabetes and complications arising in those who already have a diabetes diagnosis.

For example, in a large 2018 study, researchers found that the odds of developing type 2 diabetes increased fourfold for each percentage-unit increase in HbA1C.

Using A1C to prevent complications

People with diabetes need to manage their blood sugar levels to prevent them from becoming too high.

Managing blood sugar levels can reduce the risk of complications affecting the small blood vessels, especially of the eyes and kidneys, and the coronary arteries. This can help to prevent the many problems that can occur with diabetes, including:

vision loss
cardiovascular disease
stroke
kidney disease

Reaching and maintaining an A1C of 7% or lower can significantly reduce these risks.

However, everyone is different. An individual can work with a healthcare professional to determine their blood sugar and A1C targets.

Testing during pregnancy

A doctor may suggest an A1C test at the beginning of pregnancy. This can indicate whether or not someone with risk factors for diabetes has a high score.

Later in the pregnancy, a doctor may test for gestational diabetes in other ways, as pregnancy can affect the A1C test result.

If a person has gestational diabetes, a doctor may also test up to 12 weeks after delivery.

Test frequency

The ADA recommends regular A1C testing for people with diabetes.

For those without diabetes, the ADA recommends that anyone who is 45 years or more, or who is under 45 years but has risk factors for diabetes such as obesity, should seek a baseline test. An individual may need to attend further testing, depending on the result of their baseline test.

People who have had gestational diabetes during pregnancy may need to arrange a screening every 3 years.

Outlook

The A1C test is useful for monitoring a person’s blood sugar levels if they have diabetes and diagnosing type 2 diabetes.

It is also useful for people to perform regular blood glucose tests at home and follow the correct treatment plan for diabetes between tests.

Summary

The A1C test measures the amount of hemoglobin in the blood with glucose attached. It provides a picture of average blood sugar levels over the previous 3 months and is a valuable tool for monitoring diabetes and diagnosing type 2 diabetes.

Doctors use the A1C test to check for prediabetes and diabetes in individuals over 45. They may also use the test for younger individuals if they are overweight or have other risk factors. People living with diabetes typically have A1C tests several times per year.

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How we reviewed this article:

SourcesMedical News Today has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical journals and associations. We only use quality, credible sources to ensure content accuracy and integrity. You can learn more about how we ensure our content is accurate and current by reading our editorial policy.

A1C and eAG. (n.d.).https://www.diabetes.org/diabetes/a1c/a1c-and-eag
Abass, A. E., et al. (2017). Glycated hemoglobin and red blood cell indices in non-diabetic pregnant women. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641825
Diabetes & prediabetes tests. (2020).https://www.niddk.nih.gov/health-information/professionals/clinical-tools-patient-management/diabetes/diabetes-prediabetes
Leong. A., et al. (2018). Prediction of type 2 diabetes by hemoglobin A1C in two community-based cohorts. https://diabetesjournals.org/care/article/41/1/60/36699/Prediction-of-Type-2-Diabetes-by-Hemoglobin-A1c-in
Prediabetes and type 2 diabetes: Screening. (2021).https://www.uspreventiveservicestaskforce.org/uspstf/recommendation/screening-for-prediabetes-and-type-2-diabetes
Sherwani, S. I., et al. (2016). Significance of HbA1c test in diagnosis and prognosis of diabetic patients. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933534
All about your A1C. (2021).https://www.cdc.gov/diabetes/library/features/a1c.html
The A1C test & diabetes. (2018).https://www.niddk.nih.gov/health-information/diabetes/overview/tests-diagnosis/a1c-test

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Medically reviewed by Angelica Balingit, MD — Written by Markus MacGill and Zia Sherrell, MPH — Updated on February 14, 2023

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Từ khóa » Hg A1c

Related Topics

Causes & Risk Factors

Related Articles

Complications

Related Articles

Diagnosis

Related Articles

Diet

Related Articles

Prevention

Related Articles

Management

Related Articles

Prognosis

Related Articles

Related Conditions

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Stages

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Symptoms

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Treatment

Related Articles

What is the A1C test?

What to expect

Who should get an A1C test?

A1C results explained

What can affect A1C results?

What is eAG?

Target levels

A1C and self-monitoring

Why is testing important?

Using A1C to prevent complications

Testing during pregnancy

Test frequency

Outlook

Summary

How we reviewed this article:

Latest news

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