Thiamphenicol Drug [BSA] (DAGA-038B) - Creative Diagnostics

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Thiamphenicol Drug [BSA]

Thiamphenicol Drug BSA Conjugated, Synthetic antigen for LFIA/ELISA

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pdf COA pdf SDS pdf Datasheet Thiamphenicol [BSA], DAGA-038B - Creative Diagnostics
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Nature Synthetic Tag/Conjugate BSA Alternative Names Thiamphenicol ; Thiophenicol; thiokol Application Notes Matched pair antibody available for Thiamphenicol Drug [BSA]: Thiamphenicol Drug antibody (Catalog # HMABPY041) Format Liquid Concentration Batch dependent - please inquire should you have specific requirements. Buffer 0.01M pH7.4 PBS Preservative None Storage Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. Keywords Thiamphenicol ;Thiophenicol;thiokol Citations Have you cited DAGA-038B in a publication? Let us know and earn a reward for your research.
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Monitoring of florfenicol residues in fish muscle by HPLC-UV with confirmation of suspect results by LC-MS/MS

DRUG TESTING AND ANALYSIS

Authors: Granja, Rodrigo H. M. M.; de Lima, Andreia C.; Patel, Raj K.; Salerno, Alessandro G.; Wanschel, Amarylis C. B. A.

Abstract

Florfenicol, a derivative of thiamphenicol in which the hydroxyl group at C-3 has been replaced with fluorine, is listed by the World Health Organization as an antibacterial agent for human medicine that is critically important in risk management strategies for non-human use. AOAC International has also identified it as an important molecule for the development of effective methods for the seafood sector. Following inspection missions from the European Union and United States of America, it was introduced in the Brazilian Residues Control Program to fulfill export and internal national requirements with a Maximum Residue Limit of 800?mu g/kg. A high performance liquid chromatography method with ultraviolet detection at a wavelength of 230?nm (??=?230?nm) for the detection of florfenicol in fish muscle was developed and validated according to the Brazilian Regulation 24/2009 (equivalent to European Union Decision 2002/657/EC). Fish samples were extracted with ethyl acetate and hexane followed by C18 solid phase clean-up and chromatographic separation on a reversed-phase C18 LC column with acetonitrile:water as mobile phase. The method results were also was compared with those obtained using liquid chromatography-tandem quadrupole mass spectrometry. The method meets the Brazilian regulatory requirements with a decision limit (CCa) of 840?mu g/kg and detection capability (CC beta) of 879?mu g/kg. This method is easy to use and has been implemented into Brazil's residue control program, with liquid chromatography-tandem mass spectrometry (LC-MS/MS) confirmation of any suspect samples using the same method. (c) 2012 John Wiley & Sons, Ltd.

Simultaneous Determination of 20 Pharmacologically Active Substances in Cow's Milk, Goat's Milk, and Human Breast Milk by Gas Chromatography-Mass Spectrometry

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Authors: Azzouz, Abdelmonaim; Jurado-Sanchez, Beatriz; Souhail, Badredine; Ballesteros, Evaristo

Abstract

This paper reports a systematic approach to the development of a method that combines continuous solid-phase extraction and gas chromatography-mass spectrometry for the simultaneous determination of 20 pharmacologically active substances including antibacterials (chloramphenicol, florfenicol, pyrimethamine, thiamphenicol), nonsteroideal anti-inflammatories (diclofenac, flunixin, ibuprofen, ketoprofen, naproxen, mefenamic acid, niflumic acid, phenylbutazone), antiseptic (triclosan), antiepileptic (carbamazepine), lipid regulator (clofibric add), beta-blockers (metoprolol, propranolol), and hormones (17 alpha-ethinylestradiol, estrone, 17 beta-estradiol) in milk samples. The sample preparation procedure involves deproteination of the milk, followed by sample enrichment and cleanup by continuous solid-phase extraction. The proposed method provides a linear response over the range of 0.6-5000 ng/kg and features limits of detection from 0.2 to 1.2 ng/kg depending on the particular analyte. The method was successfully applied to the determination of pharmacologically active substance residues in food samples including whole, raw, half-skim, skim, and powdered milk from different sources (cow, goat, and human breast). Thiamphenicol Related Products
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RHA™ anti-Thiamphenicol drug residue monoclonal antibody, clone tap (HMABPY041)

RHA™ anti-Thiamphenicol drug residue monoclonal antibody, clone tap (HMABPY041)

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