Thuy Le - Scholars@Duke

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Skip to main content Thuy Le Thuy Le Associate Professor of Medicine Medicine, Infectious Diseases [email protected] Duke Box 102359, Durham, NC 27710, Durham, NC 27710 315 Trent Drive, Room #257, Durham, NC 27710 At a Glance More About This Person glance {hide_children: false, active: true, enabled: true}
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Current Appointments & Affiliations

Associate Professor of Medicine · 2024 - Present Medicine, Infectious Diseases, Medicine Associate Professor of Molecular Genetics and Microbiology · 2019 - Present Molecular Genetics and Microbiology, Basic Science Departments Affiliate, Duke Global Health Institute · 2019 - Present Duke Global Health Institute, University Institutes and Centers

In the News

Published October 16, 2025 Infographics about Antimicrobial Stewardship in Talaromyces marneffei, created by the International Society for Infectious Diseases Published February 1, 2025 Diagnosing the invasive fungal infection talaromycosis earlier to save lives Published December 9, 2024 Dr. Thuy Le, a Passionate Leader in HIV-Associated Fungal Infections in Vietnam and Worldwide: Part 2 View All News

Recent Publications

Development Framework of Desirability of Outcome Ranking Endpoints For Use in Clinical Trials of Invasive Fungal Diseases

Journal Article Open Forum Infectious Diseases · January 21, 2026 AbstractBackgroundCurrent Mycosis Study Group Education and Research Consortium (MSGERC) and European Confederation of Medical ... Full text Cite

Development and Clinical Evaluation of a Novel Talaromyces marneffei Mp1p Lateral Flow Assay for Rapid Diagnosis of Talaromycosis.

Journal Article Clin Infect Dis · January 6, 2026 BACKGROUND: The diagnosis of talaromycosis, a life-threatening invasive fungal disease endemic in Southeast Asia, still relies on protracted culture methods. We report the development and clinical evaluation of a novel lateral flow assay (LFA) for the rapi ... Full text Link to item Cite

In vitro evidence to support amphotericin B and flucytosine combination therapy for talaromycosis.

Journal Article PLoS Negl Trop Dis · December 2025 BACKGROUND: Talaromyces marneffei causes talaromycosis, a life-threatening fungal disease with limited treatment options. The standard treatment of amphotericin B (AmB) induction followed by itraconazole consolidation still results in 15% to 30% mortality. ... Full text Link to item Cite View All Publications

Recent Grants

Liposomal Amphotericin B and Flucytosine Antifungal Strategies for Talaromycosis (LAmB-FAST) - R01

ResearchPrincipal Investigator · Awarded by National Institute of Allergy and Infectious Diseases · 2024 - 2031

Interdisciplinary Research Training Program in AIDS

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2010 - 2030

Tri-Institutional Molecular Mycology and Pathogenesis Training Program

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2024 - 2029 View All Grants

Education, Training & Certifications

University of Oxford (United Kingdom) · 2016 D.Phil. University of Arizona, College of Medicine · 2002 M.D.

External Links

Oxford University Clinical Research Unit in Vietnam NIAID-funded Tropical Medicine Research Center network Tropical Medicine Research Center for Talaromycosis in Vietnam

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