Tris Hydrochloride Solution, PH 7.8 | CAS 1185-53-1 (solid) | SCBT

Trang chủ » Ph 7.8 » Tris Hydrochloride Solution, PH 7.8 | CAS 1185-53-1 (solid) | SCBT

Có thể bạn quan tâm

Date published: 2026-1-2Visit Santa Cruz Animal Health

1-800-457-3801

SCBT Portrait LogoSeach InputSearchContact UsSign In AccountQuick OrderCart (0)
  1. Home
  2. Chemicals
  3. Prepared Buffers
  4. Tris hydrochloride solution, pH 7.8/
Tris hydrochloride solution, pH 7.8 (CAS 1185-53-1 (solid)) - chemical structure image
Molecular structure of Tris hydrochloride solution, pH 7.8, CAS Number: 1185-53-1 (solid)
Tris hydrochloride solution, pH 7.8 (CAS 1185-53-1 (solid)) - chemical structure image
Molecular structure of Tris hydrochloride solution, pH 7.8, CAS Number: 1185-53-1 (solid)
Molecular structure of Tris hydrochloride solution, pH 7.8, CAS Number: 1185-53-1 (solid)Tris hydrochloride solution, pH 7.8 (CAS 1185-53-1 (solid))0.0(0)Write a reviewAsk a questionAlternate Names:Tris(hydroxymethyl)aminomethane hydrochloride solution, pH 7.8Application:Tris hydrochloride solution, pH 7.8 is non-sterile; 0.2 µm filtered, 1M stock solution used to make buffersCAS Number:1185-53-1 (solid)Molecular Weight:157.60Molecular Formula:NH2C(CH2OH)3 · HClFor Research Use Only. Not Intended for Diagnostic or Therapeutic Use.* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

Ordering InformationDescriptionTechnical InformationSafety InformationSDS & Certificate of AnalysisDescriptionTechnical InformationSafety InformationSDS & Certificate of Analysis

Tris hydrochloride, also commonly referred to as Tris-HCl, is a widely used buffer in biochemical and molecular biology applications, particularly due to its effective buffering capacity in the pH range of 7.0 to 9.0. Its utility arises from its minimal interference with biological processes, making it an invaluable tool in the study of various biochemical pathways and reactions. The pH of the solution, being precisely controlled at 7.8, optimizes the environment for numerous enzymatic and protein-related reactions. For example, Tris-HCl is often employed in gel electrophoresis protocols, where it serves as a primary component of the running buffer. It stabilizes the pH, ensuring that the molecular charge is maintained consistently during the electrophoresis, thereby affecting the migration of macromolecules like nucleic acids and proteins through a gel matrix. In molecular biology research, Tris-HCl is used in the preparation of lysis buffers which are crucial for the extraction of proteins from cells. The buffer helps maintain the structural integrity of proteins while allowing for the breakdown of cellular membranes, thus facilitating the study of intracellular processes without significant degradation or denaturation of the protein content. Furthermore, Tris-HCl plays a role in the stabilization of nucleic acids during processes such as PCR (Polymerase Chain Reaction) where it helps maintain a stable pH which is vital for the activity and integrity of the DNA polymerase. The precise control of pH at 7.8 is particularly critical in such applications, as slight deviations can lead to significant impacts on the efficiency and fidelity of the reactions.

Tris hydrochloride solution, pH 7.8 (CAS 1185-53-1 (solid)) References

  1. Towards a standardized multi-tissue decellularization protocol for the derivation of extracellular matrix materials.  |  Biehl, A., et al. 2023. Biomater Sci. 11: 641-654. PMID: 36504129

Formulation :

1 M

Physical State :

Liquid

Solubility :

Soluble in water.

pH :

7.8

Storage :

Store at room temperature

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

WGK Germany :

2

PubChem CID :

93573

MDL Number :

MFCD00012590

EC Number :

214-684-5

Beilstein Registry :

3675235

SMILES :

C(C(CO)(CO)N)O.Cl

Download SDS (MSDS)

Region

US - EnglishBrazil - PortugueseCanada - EnglishCanada - FrenchChina - ChineseEurope - EnglishEurope - FrenchEurope - GermanEurope - ItalianEurope - SpanishKorea - KoreanJapan - JapaneseMexico - SpanishSUBMIT

Certificate of Analysis

Catalog Number

sc-301952

Lot Number

​SUBMIT

How to request a Certificate of Analysis (COA) when it is not available online?

If you need a Certificate of Analysis (COA) and cannot locate it on the website, there's a straightforward process to acquire one. Here is how.

  1. Check the website sitemap before making a request to ensure you've searched all available areas where COAs may be listed.
  2. If your initial search is unsuccessful, the next step is to reach out for assistance. You can contact Customer Support via email, phone, or sometimes through a live chat feature.
  3. Simply submit a request. When you contact customer support, you will need to provide the product name, batch number, and your contact information. Explicitly state you are requesting the COA for your specific item.
  4. Remember to follow up, too. If you do not receive a response within a reasonable timeframe, don't hesitate to follow up and be sure to keep a record of your communications.

Follow these steps to get the COA you need even if it is not available online.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Tris hydrochloride solution, pH 7.8, 1 L

sc-3019521 L$30.00-+ADD TO CART
Receive special offers & announcements:SIGN UP1-800-457-3801

Customer Care

  • Contact Us
  • Ordering Information
  • Shipping Information
  • Returns and Refunds
  • Terms and Conditions
  • Promotionals
  • Investigator Awards
  • Email Settings

Resources

  • Protocols
  • Technical Service
  • Mailing List Request
  • Datasheet / SDS Request
  • Product Citation Search
  • What's New
  • Webinars

About Us

  • Careers
  • Distributors
  • Cruz Credit™ Program
  • Legal
  • Sitemap
Visit Santa Cruz Animal Health|Visit San Juan RanchSanta Cruz Animal Health is a leading provider of animal health care products. ©2025 Santa Cruz Biotechnology Inc. All Rights Reserved. Toll-Free: (800) 457-3801 - Terms & Conditions | Privacy Policy | Legal “Santa Cruz Animal Health”, “San Juan Ranch”, the San Juan Ranch logo, “UltraCruz”, “Supplement of Champions”, are registered trademarks of Santa Cruz Biotechnology, Inc. All other trademarks are the property of their respective owners.

Từ khóa » Ph 7.8