Tromethamine - The NIST WebBook

Tromethamine

• Formula: C4H11NO3
• Molecular weight: 121.1350
• IUPAC Standard InChI: InChI=1S/C4H11NO3/c5-4(1-6,2-7)3-8/h6-8H,1-3,5H2 Copy
• IUPAC Standard InChIKey: LENZDBCJOHFCAS-UHFFFAOYSA-N Copy
• CAS Registry Number: 77-86-1
• Chemical structure: This structure is also available as a 2d Mol file
• Other names: 1,3-Propanediol, 2-amino-2-(hydroxymethyl)-; Addex-Tham; Aminotrimethylolmethane; Aminotris(hydroxymethyl)methane; Methanamine, 1,1,1-tris(hydroxymethyl)-; Pehanorm; Talatrol; Tham-E; Trimethylolaminomethane; Tris; Tris amino; Tris buffer; Tris(hydroxymethyl)aminomethane; Tris(hydroxymethyl)methanamine; Tris(hydroxymethyl)methylamine; Tris-steril; Trisamin; Trisamine; Trisaminol; Trispuffer; Trizma; Trometamol; Trometamole; Tromethane; Tromethanmin; Tutofusin tris; THAM; Apiroserum Tham; Methylamine, 1,1,1-tris(hydroxymethyl)-; 2-(Hydroxymethyl)-2-amino-1,3-propanediol; 2-Amino-2-(hydroxymethyl)propane-1,3-diol; 2-Amino-2-methylol-1,3-propanediol; Tromethamin; Aminotri(hydroxymethyl)methane; TAM; Trigmo base; Triladyl; 2-Amino-2-hydroxymethylpropanediol; 2-Amino-2-(hydroxymethyl)-1,3-propanediol; Tris (hydroxymethyl)aminoethane; Tris base; Tris, free base; Trizma base; NSC 6365; Tris (buffering agent)
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• Information on this page:
  • Condensed phase thermochemistry data
  • References
  • Notes
• Other data available:
  • Phase change data
  • IR Spectrum
  • Mass spectrum (electron ionization)
  • UV/Visible spectrum
  • Gas Chromatography
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• NIST / TRC Web Thermo Tables, professional edition (thermophysical and thermochemical data)

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Condensed phase thermochemistry data

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Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.

Data compiled as indicated in comments: ALS - Hussein Y. Afeefy, Joel F. Liebman, and Stephen E. Stein DH - Eugene S. Domalski and Elizabeth D. Hearing

Quantity	Value	Units	Method	Reference	Comment
ΔfH°solid	-717.84 ± 0.82	kJ/mol	Ccr	Laynez, Ringer, et al., 1970	ALS
Quantity	Value	Units	Method	Reference	Comment
ΔcH°solid	-2426.41 ± 0.73	kJ/mol	Ccb	Xue, Wu, et al., 1985	ALS
ΔcH°solid	-2428.27 ± 0.78	kJ/mol	Ccr	Laynez, Ringer, et al., 1970	ALS
Quantity	Value	Units	Method	Reference	Comment
S°solid,1 bar	175.44	J/mol*K	N/A	Arvidsson and Westrum, 1972	DH

Constant pressure heat capacity of solid

Cp,solid (J/mol*K)	Temperature (K)	Reference	Comment
171.27	298.15	Ying and Lin, 1990	T = 290 to 450 K.; DH
167.19	298.15	Arvidsson and Westrum, 1972	T = 5 to 300 K.; DH

References

Go To: Top, Condensed phase thermochemistry data, Notes

Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.

Laynez, Ringer, et al., 1970 Laynez, J.; Ringer, B.; Sunner, S., On the accuracy of rotating-bomb combustion calorimetry for organic chlorine and bromine compounds, J. Chem. Thermodyn., 1970, 2, 603-610. [all data]

Xue, Wu, et al., 1985 Xue, R.; Wu, D.; Qu, S., Studies on thermochemistry of porphyrins. I. A precision combustion calorimetric apparatus and calibration, Wuli Huaxue Xuebao, 1985, 1, 76-81. [all data]

Arvidsson and Westrum, 1972 Arvidsson, K.; Westrum, E.F., Jr., Tris(hydroxymethane.yl)aminomethane. Heat capacities and thermodynamic properties from 5 to 350K, J. Chem. Thermodynam., 1972, 4, 449-453. [all data]

Ying and Lin, 1990 Ying, Z.Z.; Lin, Y.M., Heat capacity and phase transitions of 2-amino-2-hydroxymethylpropan-1,3-diol from 290 to 455 K, J. Chem. Thermodynam., 1990, 22, 617-622. [all data]

Notes

Go To: Top, Condensed phase thermochemistry data, References

• Symbols used in this document:

  Cp,solid	Constant pressure heat capacity of solid
  S°solid,1 bar	Entropy of solid at standard conditions (1 bar)
  ΔcH°solid	Enthalpy of combustion of solid at standard conditions
  ΔfH°solid	Enthalpy of formation of solid at standard conditions

• Data from NIST Standard Reference Database 69: NIST Chemistry WebBook
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