[Use Of Xin Bao In The Treatment Of 87 Patients With Sick Sinus ...

Clipboard, Search History, and several other advanced features are temporarily unavailable. Skip to main page content

The .gov means it’s official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation Search: Search Advanced Clipboard Save Email Send to

• Clipboard
• My Bibliography
• Collections
• Citation manager

Display options Display options Format Abstract PubMed PMID

Save citation to file

Format: Summary (text) PubMed PMID Abstract (text) CSV Create file Cancel

Email citation

Subject: 1 selected item: 2268939 - PubMed To: From: Format: Summary Summary (text) Abstract Abstract (text) MeSH and other data Send email Cancel

Add to Collections

• Create a new collection
• Add to an existing collection

Name your collection: Name must be less than 100 characters Choose a collection: Unable to load your collection due to an error Please try again Add Cancel

Add to My Bibliography

• My Bibliography

Unable to load your delegates due to an error Please try again Add Cancel

Your saved search

Name of saved search: Search terms: Test search terms Would you like email updates of new search results? Saved Search Alert Radio Buttons

• Yes
• No

Email: (change) Frequency: Monthly Weekly Daily Which day? The first Sunday The first Monday The first Tuesday The first Wednesday The first Thursday The first Friday The first Saturday The first day The first weekday Which day? Sunday Monday Tuesday Wednesday Thursday Friday Saturday Report format: Summary Summary (text) Abstract Abstract (text) PubMed Send at most: 1 item 5 items 10 items 20 items 50 items 100 items 200 items Send even when there aren't any new results Optional text in email: Save Cancel

Create a file for external citation management software

Create file Cancel

Your RSS Feed

Name of RSS Feed: Number of items displayed: 5 10 15 20 50 100 Create RSS Cancel RSS Link Copy

Actions

CiteCollectionsAdd to Collections

• Create a new collection
• Add to an existing collection

Name your collection: Name must be less than 100 characters Choose a collection: Unable to load your collection due to an errorPlease try again Add Cancel Display options Display options Format AbstractPubMedPMID

Share

• Permalink Copy

Page navigation

• Title & authors
• Abstract
• Similar articles
• Cited by
• Publication types
• MeSH terms
• Substances
• Related information

Title & authors Abstract Similar articles Cited by Publication types MeSH terms Substances Related information CiteDisplay options Display options Format AbstractPubMedPMID

Abstract

Since 1987, the authors have observed the therapeutic effect of Xin Bao on 87 patients with sick sinus syndrome. Electrophysiological stimulation examination: SNRT greater than 1900 ms and CSNRT greater than 600 ms in all patients. Routine ECG and Holter monitoring ECG: (1) Persistent sinus bradycardia or/and atrio-ventricular junction escape rhythms or/and premature beat, heart rate less than 48 +/- 6 beats/min in 40 patients; (2) sinus standstill (arrest) or secondary degree sinoatrial block in 10 patients; (3) bradycardia-tachycardia syndrome in 30 patients; (4) the heart rate greater than 60 beats/min in 7 patients. The major symptoms were dizziness, palpitation, chest press, malaise, remission in memory, nocturia, amaurosis and Adams-Stokes syndrome, etc. Self-comparison was taken, Xin Bao was given 2-10 tablets 2 or 3 times a day by oral administration for 2 months. The major symptoms of sick sinus syndrome was greatly improved after treatment. The total effective rate attaining to 85%. The improvement in heart function was also significant, the total effective rate being 80%. After treatment SNRT and CSNRT were shortened (P less than 0.01), the total heart beats for 24 hours and the average heart beats/min greatly increased (P less than 0.01). CO and EF increased too (P less than 0.05). No serious adverse reactions were found during the treatment. It was believed that Xin Bao could stimulate sino-atrial node and increase it's excitability. The basic heart rate was increased and the heart function improved with no adverse reactions. It may be administrated in long term. Therefore, Xin Bao may be recommended as appropriate drug for treating sick sinus syndrome.

PubMed Disclaimer

Similar articles

• [Research on the effect of shen xian sheng mai ye on experimental sick sinus syndrome]. Xu SQ, Wu ZM, Shi ZX. Xu SQ, et al. Zhong Xi Yi Jie He Za Zhi. 1991 Nov;11(11):674-6, 646. Zhong Xi Yi Jie He Za Zhi. 1991. PMID: 1813173 Chinese.
• [Effects of oral amezinium metilsulfate in patients with sick sinus syndrome]. Noma K, Miyazaki H, Anzawa R, Miyoshi K, Hayashi Y, Arino T, Nishide R, Seki S, Mochizuki S. Noma K, et al. J Cardiol. 1997 Jul;30(1):29-35. J Cardiol. 1997. PMID: 9253693 Japanese.
• Inhibitory effect of acute and chronic administration of digitalis on the sick sinus node. Bolognesi R, Benedini G, Ferrari R, Visioli O. Bolognesi R, et al. Eur Heart J. 1986 Apr;7(4):334-40. doi: 10.1093/oxfordjournals.eurheartj.a062071. Eur Heart J. 1986. PMID: 3720760
• [Sinus node syndrome]. Blömer H, Wirtzfeld A, Delius W, Sebening H. Blömer H, et al. Z Kardiol. 1975 Aug;64(8):697-721. Z Kardiol. 1975. PMID: 1099830 Review. German.
• Diagnosis and treatment of sick sinus syndrome. Adán V, Crown LA. Adán V, et al. Am Fam Physician. 2003 Apr 15;67(8):1725-32. Am Fam Physician. 2003. PMID: 12725451 Review.

See all similar articles

Cited by

• Herbal medicine: beneficial effects, side effects, and promising new research in the treatment of arrhythmias. Stout CW, Weinstock J, Homoud MK, Wang PJ, Estes NA 3rd, Link MS. Stout CW, et al. Curr Cardiol Rep. 2003 Sep;5(5):395-401. doi: 10.1007/s11886-003-0097-x. Curr Cardiol Rep. 2003. PMID: 12917055 Review.

Publication types

• English Abstract Actions
  • Search in PubMed
  • Search in MeSH
  • Add to Search

MeSH terms

• Aged Actions
  • Search in PubMed
  • Search in MeSH
  • Add to Search
• Drugs, Chinese Herbal / therapeutic use* Actions
  • Search in PubMed
  • Search in MeSH
  • Add to Search
• Electrocardiography, Ambulatory Actions
  • Search in PubMed
  • Search in MeSH
  • Add to Search
• Female Actions
  • Search in PubMed
  • Search in MeSH
  • Add to Search
• Humans Actions
  • Search in PubMed
  • Search in MeSH
  • Add to Search
• Male Actions
  • Search in PubMed
  • Search in MeSH
  • Add to Search
• Middle Aged Actions
  • Search in PubMed
  • Search in MeSH
  • Add to Search
• Sick Sinus Syndrome / drug therapy* Actions
  • Search in PubMed
  • Search in MeSH
  • Add to Search

Substances

• Drugs, Chinese Herbal Actions
  • Search in PubMed
  • Search in MeSH
  • Add to Search

Related information

• MedGen

[x] Cite Copy Download .nbib .nbib Format: AMA APA MLA NLM Send To

• Clipboard
• Email
• Save
• My Bibliography
• Collections
• Citation Manager

[x]

NCBI Literature Resources

MeSH PMC Bookshelf Disclaimer

The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). Unauthorized use of these marks is strictly prohibited.