C-Reactive Protein (CRP), High Sensitivity (Cardiac Risk Assessment)

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  4. 120766: C-Reactive Protein (CRP), High Sensitivity (Cardiac Risk Assessment)
C-Reactive Protein (CRP), High Sensitivity (Cardiac Risk Assessment) Test Number 120766Test number copied CPT

86141

 Synonyms
  • Cardiac C-Reactive Protein (CRP)
  • High-sensitivity CRP
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  • Print Include LOINC® in print
  • Test Details
  • Specimen Requirements
  • LOINC®

Test Details

Methodology

Immunochemiluminometric assay (ICMA)

Result Turnaround Time

Within 1 day

Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.

Related Information

  • C-Reactive Protein (CRP), Quantitative

Related Documents

For more information, please view the literature below.

Cardiovascular Care Anchor Brochure (L10222)
  • Sample Report

Use

Measurement of CRP by high sensitivity CRP assays may add to the predictive value of other markers used to assess the risk of cardiovascular and peripheral vascular disease.2-8

Special Instructions

State patient's sex on the test request form.

Limitations

Increases in CRP values are nonspecific. CRP is an indicator for a wide range of disease processes and should not be interpreted without a complete clinical history. Recent medical events resulting in tissue injury, infections, or inflammation, which may cause elevated CRP levels, should also be considered when interpreting results. Serial analysis of CRP should not be used to monitor the effects of treatment.

Specimen Requirements

Specimen

Serum or plasma

Volume

1 mL

Minimum Volume

0.5 mL (Note: This volume does not allow for repeat testing.)

Container

Red-top tube, gel-barrier tube, lavender-top (EDTA) tube, or green-top (heparin) tube

Collection Instructions

Separate serum or plasma from cells within one hour of collection.

Stability Requirements

TemperaturePeriod
Room temperature7 days
Refrigerated14 days
Frozen14 days
Freeze/thaw cyclesStable x3

Reference Range

Average hs-CRP level:1

• Low risk: <1.00 mg/L

• Average risk: 1.00−3.00 mg/L

• High risk: >3.00 mg/L

Storage Instructions

Room temperature

Causes for Rejection

Gross lipemia

Footnotes

1. Pearson TA, Mensah GA, Alexander RW, et al. Markers of inflammation and cardiovascular disease: Application to clinical and public health practice: A statement for healthcare professionals from the Centers for Disease Control and Prevention and the American Heart Association. Circulation. 2003; 107(3):499-511. 125518782. Ridker PM, Cushman M, Stampfer MJ, et al. Plasma concentration of C-reactive protein and risk of developing peripheral vascular disease. Circulation. 1998; 97(5):425-428. 94902353. Ridker PM, Cushman M, Stampfer MJ, et al. Inflammation, aspirin, and the risk of cardiovascular disease in apparently healthy men. N Engl J Med. 1997; 336(14):973-979. 90773764. Ridker PM, Buring JE, Shih J, et al. Prospective study of C-reactive protein and the risk of future cardiovascular events among apparently healthy women. Circulation. 1998; 98(8):731-733. 97275415. Ridker PM, Glynn RJ, Hennekens CH. C-Reactive protein adds to the predictive value of total and HDL cholesterol in determining risk of first myocardial infarction. Circulation. 1998; 97(20):2007-2011. 96105296. Ridker PM, Rifai N, Peffer MA, et al, for the Cholesterol and Recurrent Events (CARE) Investigators. Inflammation, pravastatin, and the risk of coronary events after myocardial infarction in patients with average cholesterol levels. Circulation. 1998; 98(9):839-844. 97386377. Tracy RP, Lemaitre RN, Psaty BM, et al. Relationship of C-reactive protein to risk of cardiovascular disease in the elderly: Results from the Cardiovascular Health Study and the Rural Health Promotion Project. Arterioscler Thromb Vasc Biol. 1997; 17(6):1121-1127. 91947638. Macy EM, Hayes TE, Tracy RP. Variability in the measurement of C-reactive protein in healthy subjects: Implications for reference interval and epidemiological applications. Clin Chem. 1997; 43(1):52-58. 8990222

LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
120766 C-Reactive Protein, Cardiac 30522-7 120768 C-Reactive Protein, Cardiac mg/L 30522-7
Order Code120766
Order Code NameC-Reactive Protein, Cardiac
Order Loinc30522-7
Result Code120768
Result Code NameC-Reactive Protein, Cardiac
UofMmg/L
Result LOINC30522-7

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