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When zoo worker Frank Detorre (Bill Murray) contracts the virulent virus Thrax (voice of Laurence Fishburne), inside his body--known as "The City of Frank" to its inhabitants--a white blood cell cop, Osmosis Jones (voice of Chris Rock), and a cold tablet, Drix (voice of David Hyde Pierce), join forces to fight the invading virus intent on taking over "The City." But to bust Thrax, Osmosis Jones must bypass Mayor Phlegmming (voice of William Shatner) and enlist the aid of the Mayor's assistant, Leah (voice of Brandy Norwood). When Osmosis and Thrax clash in the climactic battle of this germ warfare, Frank's life--and the lives of all the citizens of The City of Frank--hang in the balance.This action-adventure comedy combines live action with state-of-the-art animation.

 2001 · 1h 35m
Starring Bill Murray, Molly Shannon, Chris Elliott Director Peter Farrelly, Robert Farrelly

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Osmosis Jones

Comedy

When zoo worker Frank Detorre (Bill Murray) contracts the virulent virus Thrax (voice of Laurence Fishburne), inside his body--known as "The City of Frank" to its inhabitants--a white blood cell cop, Osmosis Jones (voice of Chris Rock), and a cold tablet, Drix (voice of David Hyde Pierce), join forces to fight the invading virus intent on taking over "The City." But to bust Thrax, Osmosis Jones must bypass Mayor Phlegmming (voice of William Shatner) and enlist the aid of the Mayor's assistant, Leah (voice of Brandy Norwood). When Osmosis and Thrax clash in the climactic battle of this germ warfare, Frank's life--and the lives of all the citizens of The City of Frank--hang in the balance.This action-adventure comedy combines live action with state-of-the-art animation.

COMMON SENSE

Mostly animated PG film has gross-out humor, violence.

TOMATOMETER
Average 5.9
Reviews 111
Fresh 61
Rotten 50

Information

Studio Warner Bros.Released 2001Run Time 1 hr 35 minRated PG For bodily humor. (Re-rated from PG-13)Region of Origin United States © 2001 Warner Bros. Entertainment Inc. All Rights Reserved.

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Original Audio EnglishAudio

English (United States) (AAC, ⁨Dolby 5.1⁩), French (Canada) (AAC)

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English (CC)

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