Bio-inspired Dynamic Biomolecule Assembling For Fine Regulation Of ...
Bio-inspired dynamic biomolecule assembling for fine regulation of protein activity†
Wenxiao Wang,‡ab Yu Shen,‡a Fuan Wang, 
a Ying Liu*a and Xiaoqing Liu *a Author affiliations * Corresponding authors
a College of Chemistry and Molecular Sciences, Wuhan University, Wuhan, P. R. China E-mail: [email protected], [email protected]
b College of Chemistry and Chemical Engineering, Linyi University, Linyi, P. R. China
Abstract
A versatile approach for the fine control of DNA-based hierarchical assembly via dual stimuli and two assembly strategies is developed. Moreover, with a reasonable design of functional thrombin aptamer structures on the formed DNA nanoassembly, it can achieve precise regulation of thrombin activity.
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