Why DNA + Protein Single-cell Multi-omics? - Mission Bio

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Thank you! Your submission has been received! Oops! Something went wrong while submitting the form. CLOSE X HOME CAPABILITIES Why Single Cell? SNV SNV + CNV DNA + Protein Applications Oncology Research Multiple Myeloma Acute Myeloid Leukemia Precision Medicine Genome Editing Genome Integrity Assay Biomarker Development Cell and Gene Therapy Products & Services Tapestri Platform Panels Pharma Assay Development PAD for Cell & Gene Therapy PAD for Drug Development RESOURCES BLOG PODCAST COMPANY About Us Careers Newsroom Events Distributors & Service Providers SUPPORT CENTER CONTACT PORTAL X Mission Bio Logo COMPANY SUPPORT CENTER CONTACT PORTAL SEARCH MENU Why Single Cell? Why Single Cell? Single-cell Genomics SNV SNV + CNV Single-cell Multi-omics DNA + Protein Oncology Research Hematologic Malignancies Solid Tumors Multiple Myeloma Acute Myeloid Leukemia Precision Medicine Biomarker Development Cell and Gene Therapy Pharma Assay Development Genome Editing Genome Editing Genome Integrity Assay Genome Integrity Assay Panels Tapestri Platform Pharma Assay Development PAD for Cell & Gene Therapy PAD for Drug Development Library icon LIBRARY All Resources Scientific Presentations Researcher Spotlights Videos Brochures Datasets User Guides Technical Notes Posters Drop-Lit icon Publications LEARNING CENTER *NEW: Beyond Bulk Sequencing: Uncovering Clonal Heterogeneity with Single-Cell Multiomic Cancer Profiling Drop-Lit icon BLOG On The Drop icon PODCAST About Us Careers Newsroom Events Distributors & Service Providers Home Capabilities DNA + Protein DNA + ProteinFind the key signatures of cancer through single-cell multi-omics.

You seek more than patterns. You seek the sources of disease. The Tapestri Platform analyzes genotype and phenotype simultaneously from single cells, revealing the heterogeneity of your samples with unprecedented resolution. Leverage single-cell multi-omics to target comprehensive biomarkers that help stratify patients more precisely, signal resistance as it begins, and predict relapse.

View VideoDownload App Note Key Benefits CASE STUDY Applications Workflow DATASETS RESOURCES

Why DNA + Protein Single-cell Multi-omics?

Cancer is a complex disease with a mix of cells in varied states. Understanding the effect of genotype on immunophenotype at the single-cell level reveals disease processes and ultimately enables better therapies. A single-cell multi-omics approach is the only way to achieve full resolution of tumor heterogeneity. Perform true multi-omics with simultaneous detection of SNVs, CNVs, and cell-surface proteins at the single-cell level. DNA helix icon Correlate immunophenotype with genotype from the same cell. cancer cell icon Distinguish subclones from minimal residual disease with single-cell multi-omics based on SNVs, CNVs, and protein expression. single cell with nucleus and DNA icon Eliminate inferences while saving on research budgets and analysis times.

Explore insights of single-cell multi-omics in myeloid malignancies

Ross Levine, MD, Memorial Sloan Kettering Cancer Center

Watch Video View Panels Target the diversity that matters with content in a custom panel, or start with one of our pre-designed panels. LEARN MORE Explore Hematology See how single-cell DNA sequencing transforms the study of hematological malignancies. LEARN MORE

The Tapestri Workflow

Integrate seamlessly into your existing NGS workflow with sample prep and analysis solutions using the Tapestri single-cell sequencing platform

With our single-cell sequencing platform, use the Tapestri Instrument, reagents, and consumables up-front of your NGS system and then Tapestri Pipeline and Tapestri Insights software for data analysis and visualization. Target Selection Choose a pre-designed or custom DNA panel primer and DNA fragment alignment icon Pre-designed DNA Panels Custom DNA Panels with Tapestri Designer SAMPLEPREP Add a protein panel and simple cell staining protocol microtube with mixed population of cells icon Protein Panels LIBRARYPREP Single workflow combines DNA and protein panels Tapestri Platform icon Tapestri Instrument SEQUENCING Single sequencing run for multi-omics single-cell data next-generation sequencing platform icon PIPELINE Integrated pipeline for multi-omics analysis Tapestri Pipeline Software icon Tapestri Pipeline ANALYSIS Powerful analysis and visualization software monitor with plots icon Tapestri Insights

Datasets

Explore the datasets below using single-cell multi-omics analysis.

NAME DESCRIPTION LAST UPDATED 4 Cell Line Mix for SNV, CNV, and Protein Multi-omics Analysis

Sample dataset for the Tapestri Single Cell DNA AML panel

12.22.2021 OTHER CAPABILITIES

DNA Is Our Foundation

Providing cancer specialists with the only single-cell targeted DNA solution that integrates SNV, CNV, and protein data from the same cell.

Single-cell Genomics (DNA) SNV Detect rare clonal populations and identify co-occurrence and zygosity. LEARN MORE SNV + CNV Characterize genomic heterogeneity using a single comprehensive platform. LEARN MORE

Featured Resources

technical note Correlations between genomic variants and protein expression in AML patient samples LEARN MORE ebook Single-cell Sequencing 101: DNA & multi-omics for precision medicine LEARN MORE spotlight Immune-Based Therapies for Hematology: Single-cell Multi-omics and Cell Therapies for Leukemias LEARN MORE ALL RESOURCES

Ready to build your DNA + Protein panel?

Chat with one of our design experts to build a panel to simultaneously detect SNVs, CNVs, and protein expression.

CONTACT US HEADQUARTERS 300 Utah Avenue, Suite 210South San Francisco, CA, 94080 +1 (415) 854-0058 [email protected] ©2025 Mission Bio. All Rights Reserved. SIGN UP FOR PRODUCT AND EVENT UPDATES Thank you! Your submission has been received! Oops! Something went wrong while submitting the form. CAPABILITIES Why Single Cell? SNV SNV + CNV DNA + Protein APPLICATIONS Oncology Research Multiple Myeloma Acute Myeloid Leukemia Precision Medicine Genome Editing Biomarker Development Cell and Gene Therapy PRODUCTS & SERVICES Tapestri Platform Panels Pharma Assay Development PAD for Cell & Gene Therapy PAD for Drug Development COMPANY CAREERS NEWSROOM EVENTS BLOG RESOURCES SUPPORT CENTER CONTACT Terms of Use Privacy Policy Terms and Conditions of Sale Client Data Security & Retention REQUEST QUOTE

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