C 021 Dihydrochloride | CAS 1784252-84-1 | SCBT
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Ordering InformationDescriptionTechnical InformationSafety InformationSDS & Certificate of AnalysisDescriptionTechnical InformationSafety InformationSDS & Certificate of AnalysisA potent CCR4 chemokine receptor antagonist (IC50 values are 0.14 and 0.039 μM for inhibition of chemotaxis in human and mouse respectively)
C 021 dihydrochloride (CAS 1784252-84-1) References
Yokoyama et al (2009) Potent and orally bioavailable CCR4 antagonists: synthesis and structure-activity relationship study of 2-aminoquinazolines. Bioorg.Med.Chem. 17 64.Inhibitor of:CKR-4.
Read morePhysical State :
Solid
Solubility :
Soluble in water (50 mM), and DMSO (100 mM).
Storage :
Desiccate at room temperature
IC50 :
CCR4 chemokine receptor: IC50 = 0.14 µM (human); CCR4 chemokine receptor: IC50 = 0.039 µM (mouse); CCL22-binding: IC50 = 73 nM; CCL22-induced GTPγS recruitment: IC50 = 18 nM
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use. Available in US only.Transport :
Not available for sale outside of the United States.
PubChem CID :
56972238MDL Number :
MFCD16618393
SMILES :
COC1=C(C=C2C(=C1)C(=NC(=N2)N3CCC(CC3)N4CCCCC4)NC5CCCCCC5)OC.Cl.Cl
Download SDS (MSDS)
Region
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C 021 dihydrochloride | CAS 1784252-84-1 SAMPLE Certificate of AnalysisCertificate of Analysis
Catalog Number
sc-293973sc-293973ALot Number
SUBMITSAMPLE Certificate of Analysis (COA)
Catalog Number:sc-293973Lot Number:SAMPLEProduct Name:C 021 dihydrochlorideMolecular Formula:C27H41N5O2•2HClMolecular Weight:540.57| Test | Specification | Results |
|---|---|---|
| Appearance | Pale yellow solid | |
| Identification (1H-NMR) | Consistent with structure | |
| Identification (Mass Spectrometry) | Consistent with structure | |
| Purity (HPLC) | 99.6% | |
| TLC | Rf = 0.4 (Dichloromethane: Methanol [4: 1]) | |
| Carbon Content | 58.06% | 58.09% |
| Hydrogen Content | 8.12% | 8.13% |
| Nitrogen Content | 12.54% | 12.51% |
TEST CONDITIONS
Exp. Date: 9/4/2024
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Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
C 021 dihydrochloride, 10 mg | sc-293973 | 10 mg | $210.00 | -+ | ADD TO CART | |
| US: Only available in the US | ||||||
C 021 dihydrochloride, 50 mg | sc-293973A | 50 mg | $880.00 | -+ | ADD TO CART | |
| US: Only available in the US | ||||||
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