c-Cbl and Cbl-b are prominent substrates of PTKs, and both are phosphorylated following the stimulation of a diverse array of cell-surface receptors. c-Cbl ... Abstract · DOMAIN STRUCTURE AND... · c-CBL AND CBL-B IN...
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23 May 2019 · Casitas B-lineage lymphoma (c-Cbl) is a member of the CBL family of proteins and is comprised of three homologues [28,29]. c-Cbl is an ... c-Cbl Family of Ubiquitin E3... · c-Cbl as a Major Regulator of... · c-Cbl in Retinal...
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7 Jul 2009 · Adapter protein that functions as a negative regulator of many signaling pathways that are triggered by activation of cell surface receptors ...
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Cbl is a mammalian gene encoding the protein CBL which is an E3 ubiquitin-protein ligase involved in cell signalling and protein ubiquitination. Discovery · Structure · Homologues · Interactions
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27 Dec 2019 · Casitas B lymphoma (c-Cbl) is an E3 ubiquitin ligase and a negative regulator of colorectal cancer (CRC). Despite its high expression in ...
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4 Nov 2002 · c-Cbl and Cbl-b are two members of the mammalian Cbl family. They are expressed in hematopoietic cells and share structural similarities ...
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6 Jun 2022 · This gene is a proto-oncogene that encodes a RING finger E3 ubiquitin ligase. The encoded protein is one of the enzymes required for ...
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US$287.00 In stock Polyclonal Antibody for studying Cbl. Cited in 29 publications. Validated for WB, IP, IF. Highly specific and rigorously validated in-house, c-Cbl Antibody ...
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24 Feb 2015 · The E3 ligase c-Cbl has been identified as a modulator of DC activation (118). Toll-like receptor (TLR)-induced expression of pro-inflammatory ...
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28 Oct 2020 · Figure 2. c-Cbl is a cellular negative regulator of HIV-1 Nef protein. (A) HEK293T cells were co-transfected with the vectors to express FLAG ...
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Ubiquitination of receptor protein-tyrosine kinases (RPTKs) terminates signaling by marking active receptors for degradation. c-Cbl, an adapter protein for ...
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US$335.00 Human c-CBL, also known as CBL-2, Cbl Proto-Oncogene, Signal Transduction Protein CBL, and Cbl Proto-Oncogene, E3 Ubiquitin Protein Ligase, ...
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c-Cbl Protein, active, 10 µg Active, full length, recombinant human c-Cbl. N-terminal GST-tagged. For use in Enzyme Assays. Functions as an E3 ligase in ...
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V-Cbl is found in the nucleus of transformed cells. C-Cbl is associated with the Grb2 adapter protein and is phosphorylated upon tyrosine residues following ...
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