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C4X Discovery Ltd

Biotechnology Research

Pioneering drug discovery company exploiting cutting edge technologies to create best-in-class small molecule medicines

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About us

C4XD is a pioneering Drug Discovery company, combining scientific expertise with cutting-edge technologies to efficiently deliver world‑leading medicines. We have a highly valuable and differentiated approach to Drug Discovery through our enhanced molecular design and patient stratification capabilities, generating small molecule drug candidates across multiple disease indications focused on immuno-inflammation. The Company was founded as a spin-out from the University of Manchester. It has a highly experienced management team and Board who have delivered significant value creation within the healthcare sector historically and have enabled C4XD to reach multiple value inflexion points since IPO. Website: www.c4xdiscovery.com Twitter: @C4XDiscovery

Website http://www.c4xdiscovery.com/

External link for C4X Discovery Ltd

Industry Biotechnology Research Company size 11-50 employees Headquarters Manchester Type Privately Held Founded 2008 Specialties Drug Discovery, NMR, and Data Science

Locations

• Primary

  Manchester One

  53 Portland Street

  Manchester, M1 3LD, GB

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• London, London NW1 1AD, GB

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Employees at C4X Discovery Ltd

• DAVID LAWRENCE

• Nick Ray

• Richard CM Jones

• Diane Geraghty

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Updates

• C4X Discovery Ltd

  5,304 followers

  1mo
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  Looking forward for #BIOEuropeFall next week in the beautiful city of Vienna. Nick Ray and Flora Shimi will be sharing more about our a4b7 inhibitor candidate and exciting updates on our PAD4 and TNFa small molecule inhibitor programs #drugdiscovery #smallmolecule #immunology

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• C4X Discovery Ltd

  5,304 followers

  2mo
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  We're excited to be at ACR Convergence 2025 in Chicago this week! Shilina Roman and Flora Shimi are looking forward to connecting with the rheumatology community. Drop us a line if you're attending #ACR25 and would like to connect #Rheumatology #DrugDiscovery #ImmunoInflammation

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• C4X Discovery Ltd

  5,304 followers

  3mo
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  Today, we announced the selection of a potential best-in-class once-daily development candidate from our oral α4β7 integrin inhibitor programme for the treatment of inflammatory bowel disease (IBD). With over five million people worldwide living with IBD and many still underserved by existing therapies, C4X Discovery’s oral α4β7 inhibitor could provide a more accessible, personalised, and effective option for patients. Read the full announcement here: https://lnkd.in/eZt6Zcde #C4XD #DrugDiscovery #Biotech #IBD #OralTherapies

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• C4X Discovery Ltd

  5,304 followers

  4mo Edited
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  We're excited for Neil Humphryes-Kirilov to present to the world-class research community at the 20th anniversary of the Biomarkers & Precision Medicine conference next month in London, sharing insights on a genomic signature for drug response in Ulcerative Colitis #BIOMUK2025

  Neil Humphryes-Kirilov 4mo

  I'm thrilled to be joining an incredible lineup of experts at the Biomarkers & Precision Medicine 2025 conference, happening 30 September – 1 October in London, UK. I'll be speaking on precision medicine for Ulcerative Colitis, sharing insights on predictive biomarkers of drug response. This event is a must-attend for anyone passionate about the future of precision medicine, biomarker discovery, and translational science.  Register now to secure your spot and be part of the conversation: https://lnkd.in/g97FcsAw Looking forward to connecting with you in London! #BIOMUK2025

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• C4X Discovery Ltd

  5,304 followers

  6mo
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  Looking forward to #BIO2025 where our CSO Nick Ray and BD Manager Emma Thomas will be representing us in Boston from June 16-19. Don't hesitate to get in touch if you'd like to meet up at the conference. #biotech #immunology

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• C4X Discovery Ltd

  5,304 followers

  7mo
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  Today, we announced an €8 million milestone payment from Sanofi following pre-clinical progress in the ongoing oral IL-17A inhibitor programme, which has the potential to transform treatment options for patients living with debilitating inflammatory diseases. This latest payment is part of an existing license agreement, in which C4X is entitled to up to €414 million in upfront milestone payments. Read the full announcement here: https://lnkd.in/eRUjCfAz #C4XD #Partnership #Biotech #Innovation

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• C4X Discovery Ltd

  5,304 followers

  7mo
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  We're excited to share Neil Humphryes-Kirilov will be participating in a panel discussion on the 14th May at the 3rd Precision Medicine in Inflammatory Bowel Disease Summit in #Boston Will be a fascinating and ambitious discussion covering a wide range of critical topics on the future of Precision Medicine in IBD. Hear about therapeutic modalities, combo therapies, the opportunities to improve patient outcomes using precision medicine and the challenges that need to be overcome to get there Join him over the course of the summit and also for our poster discussing our exciting work using PatientSeek to develop a genomic signature of response to a4b7 targeted therapy in Ulcerative Colitis #PrecisionMedicineinIBD #PrecisionMedicine #UlcerativeColitis

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• C4X Discovery Ltd

  5,304 followers

  9mo Edited
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  Looking forward to Bio-Europe 2025 next week where Nick Ray and Emma Thomas will have exciting updates on advancements to our transformative portfolio of precision oral programmes in immuno-inflammation and our innovative drug discovery platforms #BIOEuropeSpring #biotech #precisionmedicine #immunology

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• C4X Discovery Ltd

  5,304 followers

  10mo
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  We're excited for Shilina Roman and Flora Shimi to represent C4X Discovery Ltd in Berlin this week for #ECCO2025 to learn how the future is unfolding in #IBD. Great to connect with the community, both familiar faces and new! Fascinating to see the adoption of new technologies and approaches to precision medicine, in both clinical research and practice. A key theme is #biomarkers for predicting response to advanced therapy. We're energised to be contributing to the development of the field with our PatientSeek stratification signature for our oral a4b7 inhibitor. If you're in Berlin too, drop a line to Shilina or Flora for a coffee between sessions to learn more! #IBD #PrecisionMedicine #Biotech

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• C4X Discovery Ltd

  5,304 followers

  11mo
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  We are pleased to announce the appointment of DAVID LAWRENCE as Interim Non-Executive Chairman of C4X Discovery. Clive Dix.HonFBPhS steps down after an outstanding decade of leadership who, during his tenure, has driven the evolution of C4XD into a leading immuno-inflammatory therapeutics company. David brings extensive expertise, having overseen multiple fundraisings and transactions across global markets. Under David’s leadership, C4XD will continue to build on its strong foundation, progressing its pipeline and delivering on its strategic objectives. We thank Clive for his vision and dedication, which have been instrumental in positioning C4XD at the forefront of drug discovery. https://lnkd.in/dqutjwKC  #C4XDiscovery #Drugdiscovery #precisionmedicine”

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Funding

C4X Discovery Ltd 2 total rounds

Last Round

Post IPO equity Oct 6, 2016 External Crunchbase Link for last round of funding

US$ 6.7M

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