Top 14+ Cc-115 hay nhất
-
1.CC-115 | ≥99%(HPLC) | Selleck | DNA-PK Inhibitor
Rating 5.0 (8) Description, CC-115 is a dual inhibitor of DNA-dependent protein kinase (DNA-PK) and mammalian target of rapamycin (mTOR) with IC50 values of 0.013 μM and 0.021 ...
Xem chi tiết » -
2.CC-115, A Dual Inhibitor Of MTOR Kinase And DNA-PK ... - NCBI
CC-115 is a dual mTOR kinase/DNA-PK inhibitor with little activity against ATM and ATR in purified enzyme assays [26]. We report here that CC-115 inhibits both ... INTRODUCTION · RESULTS · DISCUSSION · MATERIALS AND METHODS
Xem chi tiết » -
3.Cc-115 | C16H16N8O - PubChem
DNA-PK/TOR Kinase Inhibitor CC-115 is a dual inhibitor of DNA-dependent protein kinase (DNA-PK) and mammalian target of rapamycin (mTOR), with potential ...
Xem chi tiết » -
4.DNA-PK/TOR Kinase Inhibitor CC-115 - National Cancer Institute
CC-115 binds to and inhibits the activity of DNA-PK and both raptor-mTOR (TOR complex 1 or TORC1) and rictor-mTOR (TOR complex 2 or TORC2), which may lead ...
Xem chi tiết » -
5.CC 115 - AdisInsight - Springer
CC 115, an orally active dual kinase inhibitor is being developed by Celgene Corporation (a subsidiary of Bristol Myers Squibb) is developing, ...
Xem chi tiết » -
6.Study To Assess Safety And Tolerability Of Oral CC-115 For Patients ...
The main purpose of this first human study with CC-115 is to assess the safety and action of a new class of experimental drug (dual DNA-PK and TOR kinase ...
Xem chi tiết » -
7.CC-115 Hydrochloride | DNA-PK/mTOR Inhibitor - MedChemExpress
Rating 5.0 (1) CC-115 hydrochloride is a potent and dual DNA-PK and mTOR kinase inhibitor with IC50s of 13 nM and 21 nM, respectively. CC-115 blocks both mTORC1 and mTORC2 ...
Xem chi tiết » -
8.An MTOR And DNA-PK Dual Inhibitor CC-115 Hinders Non-small Cell ...
18 Jun 2022 · Molecularly-targeted agents are still urgently needed for better non-small cell lung cancer (NSCLC) therapy. CC-115 is a potent ...
Xem chi tiết » -
9.De Havilland Canada DHC-5 Buffalo - Wikipedia
DehavillandCC-115Buffalo12.JPG. A CC-115 Buffalo of 442 Transport & Rescue Squadron at Rockcliffe Airport in Ottawa, 2004. Role, Utility aircraft.
Xem chi tiết » -
10.CC-115 Buffalo Canadian AF Aircraft (de Havilland) 1/144 Amodel ...
CC-115 Buffalo Canadian AF aircraft (de Havilland) 1/144 Amodel 1418 : Amazon.sg: Toys.
Xem chi tiết » -
11.CC-115 - Inxight Drugs
CC-115 is a recently identified inhibitor of the mammalian Target of Rapamycin Kinase (TORK) and DNA-Dependent Protein Kinase (DNA-PK).
Xem chi tiết » -
12.CC-115 Buffalo - Royal Canadian Air Force Aircraft
The CC-115 Buffalo aircraft flew an impressive 55 years in the Royal Canadian Air Force from 1967 to 2022. The first CC-115s were stationed at 429 Squadron ...
Xem chi tiết » -
13.Final Operational Flight Of The CC-115 Buffalo Aircraft
15 Jan 2022 · On August 9, 1974, a CC115 Buffalo (CC1155461) was shot down by Syrian anti-aircraft missiles while on United Nations duty supporting ...
Xem chi tiết » -
14.CC-115, A Dual Mammalian Target Of Rapamycin/DNA-Dependent ...
CC-115, a Dual Mammalian Target of Rapamycin/. DNA-Dependent Protein Kinase Inhibitor in Clinical Trial, Is a Substrate of ATP-Binding Cassette G2, ...
Xem chi tiết »