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Featured Article

Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome

Published: May 15, 2020

The genome assembly for the Chinese hamster was further improved and now contains chromosome-scale scaffolds. Long-range scaffolding of the previous CH genome assembly (PICR) was performed using high-throughput chromosome conformation capture to create this significantly more continuous CH assembly (referred to as PICRH).

see previous articles

News

Updated chromosome-scale CH assembly and CH/CHO-K1 annotations

January 27, 2021

A significantly more continuous version of the Chinese hamster genome, CH PICRH (GCF_003668045.3), along with its 2020 RefSeq annotation is now on CHOgenome.org. Long-range scaffolding of the previous CH genome assembly was performed using high-throughput chromosome conformation capture (Hi-C) and now 97% of the genome is contained in 11 large scaffolds corresponding to the CH chromosomes. In addition, the updated 2020 RefSeq annotation for the CHO-K1 cell line is available. Both can be searched (gene search and BLAST) and viewed on JBrowse. More information on the most recent version of the Chinese hamster genome can be found here.

Updated CH assembly and CH/CHO-K1 annotations

May 1, 2019

We are excited to announce that the significantly improved Chinese hamster genome, CH PICR (GCF_00366804.1), along with its 2018 RefSeq annotation is now online. In addition, an updated RefSeq annotation for the CHO-K1 cell line is now available. Both can be searched (gene search and BLAST) and viewed on JBrowse. More information on the updated Chinese hamster genome can be found here.

New mRNA Expression Browser (Beta)

June 7, 2017

The browser (beta version) for the visualization of mRNA expression from CHO-K1 cells is now online. The data is from several published DNA-microarray or RNA-Seq experiments. The tutorial on how to use this browser can be found here.

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Search RefSeq

Search the RefSeq CHO-K1 and Chinese hamster assemblies by gene name, symbol, gene ID, or transcript RefSeq ID:

For detailed searches use Advanced Search

Welcome to the CHO Genome website! Tutorials for how to use this website can be viewed here and we welcome any questions or suggestions you may have.

Updates and details regarding the CHOStart project can be found here:

CHOStart

Access CHOmine, the CHO and Chinese hamster InterMine site:

CHOmine

Gene Search Search the RefSeq Chinese Hamster and CHO-K1 assemblies	BLAST BLAST sequences against Chinese Hamster or CHO-K1 genomes	Genome Viewer View the annotated RefSeq Chinese Hamster or CHO-K1 genomes
Proteome Browser Search the 2-D gel and shotgun datasets	Downloads Useful Chinese Hamster publications and files	CH Genome Viewer View the chromosome-sorted Chinese Hamster genome

Events

Previous Events

Mammalian Systems Biotechnology Workshop

Singapore

August 11 - August 12, 2016

This workshop will bring together globally eminent experts actively working in the Mammalian Systems Biotechnology field, in order to share and discuss state-of-the-art developments and their industrial applications.

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Cell Culture Engineering XV

La Quinta, California, USA

May 8 - May 13, 2016

The Cell Culture Engineering XV conference will bring together about 350 selected participants from top academic, industrial and governmental groups from all over the world.

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251st ACS National Meeting & Exposition

San Diego, CA, USA

March 13 - March 17, 2016

The 251st ACS National Meeting & Exposition in San Diego, CA will convene from March 13 - 17, 2016 and the BIOT division will focus on the exchange of information among academic and industrial researchers regarding technology utilizing life-based systems to produce useful products and services.

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