Dr Albert Bo XUE - SynCTI

Skip to content

+65 6601 2449 | [email protected]

SynCTIToggle Navigation Dr Albert Bo XUE Dr Bo XUEDarius Pastrana2020-03-16T19:12:40+08:00 Dr Albert Bo XUEResearch Assistant Professor[email protected]

Affiliations

Research Assistant Professor, Department of Biochemistry, Yong Loo Lin School of Medicine, NUS Research Cluster Lead, Wilmar-NUS Corporate Laboratory (Wil@NUS) Principle Investigator, NUS Synthetic Biology for Clinical and Technological Innovation (SynCTI)

Biodata

XUE Bo obtained his Ph.D in Biochemical Engineering from Tianjin University, China, and received training on protein X‐ray crystallography at the Biomedical Centre of Uppsala University, Sweden. He has broad interests in both basic and applied research, and has made significant contributions to various projects on actin-binding proteins, self-assembling peptides and enzymes. His current research focuses on deciphering the structure-function relationship of novel enzymes, and on the application of these enzymes in synthetic biology. He received and participated in two competitive research programmes. He has published over 30 peer-reviewed articles. He serves as a reviewer for international journals such as Biotechnology for Biofuels, Applied Biochemistry and Biotechnology, & 3 Biotech.

Research Interest

Structure-guided protein engineering and rational design of enzymes.

Selected Publications

  1. Go M#, Zhao L#, Xue B#, Robinson RC, Fan H, Yew WS (2020) Directed computational evolution of quorum-quenching lactonases from the amidohydrolase superfamily. Structure, submitted.
  2. Szatmári D, Xue B, Kannan B, Burtnick LD, Bugyi B, Nyitrai M, Robinson RC (2018). ATP competes with PIP2 for binding to gelsolin. PLoS ONE 13, e0201826.
  3. Chan KH, Xue B, Robinson RC, Hauser CAE (2017). Systematic Moiety Variations of Ultrashort Peptides Produce Profound Effects on Self-Assembly, Nanostructure Formation, Hydrogelation, and Phase Transition. Scientific Reports 7, 12897.
  4. Sun H, Yeo WL, Lim YH, Chew X, Smith DJ, Xue B, et al. (2016) Directed evolution of a fluorinase for improved fluorination efficiency with a non-native substrate. Angew Chem Int Ed Engl 55, 14277–14280.
  5. Xue B*#, Leyrat C#, Grimes JM, Robinson RC (2014) Structural basis of thymosin- beta4/profilin exchange leading to actin filament polymerization. Proc Natl Acad Sci USA 111: E4596-4605.
  6. Chow JY#, Xue B#, Lee KH, Tung A, Wu L, et al. (2010) Directed evolution of a thermostable quorum-quenching lactonase from the amidohydrolase superfamily. J Biol Chem 285: 40911-40920.

* Corresponding author; # Co-first author

Page load link
This site uses cookies
We use cookies on our website to give you the most relevant experience by remembering your preferences and repeat visits. By clicking “Accept” or continuing to use this site, you consent to the use of ALL the cookies. For more details about cookies and how to manage them, please see our Privacy Notice. .Cookie SettingsAcceptManage consent Close

Privacy Overview

This website uses cookies to improve your experience while you navigate through the website. Out of these, the cookies that are categorized as necessary are stored on your browser as they are essential for the working of basic functionalities of the website. We also use third-party cookies that help us analyze and understand how you use this website. These cookies will be stored in your browser only with your consent. You also have the option to opt-out of these cookies. But opting out of some of these cookies may affect your browsing experience. Necessary Necessary Always Enabled Necessary cookies are absolutely essential for the website to function properly. These cookies ensure basic functionalities and security features of the website, anonymously.
CookieDurationDescription
cookielawinfo-checkbox-analytics11 monthsThis cookie is set by GDPR Cookie Consent plugin. The cookie is used to store the user consent for the cookies in the category "Analytics".
cookielawinfo-checkbox-functional11 monthsThe cookie is set by GDPR cookie consent to record the user consent for the cookies in the category "Functional".
cookielawinfo-checkbox-necessary11 monthsThis cookie is set by GDPR Cookie Consent plugin. The cookies is used to store the user consent for the cookies in the category "Necessary".
cookielawinfo-checkbox-others11 monthsThis cookie is set by GDPR Cookie Consent plugin. The cookie is used to store the user consent for the cookies in the category "Other.
cookielawinfo-checkbox-performance11 monthsThis cookie is set by GDPR Cookie Consent plugin. The cookie is used to store the user consent for the cookies in the category "Performance".
viewed_cookie_policy11 monthsThe cookie is set by the GDPR Cookie Consent plugin and is used to store whether or not user has consented to the use of cookies. It does not store any personal data.
Functional Functional Functional cookies help to perform certain functionalities like sharing the content of the website on social media platforms, collect feedbacks, and other third-party features. Performance Performance Performance cookies are used to understand and analyze the key performance indexes of the website which helps in delivering a better user experience for the visitors. Analytics Analytics Analytical cookies are used to understand how visitors interact with the website. These cookies help provide information on metrics the number of visitors, bounce rate, traffic source, etc. Advertisement Advertisement Advertisement cookies are used to provide visitors with relevant ads and marketing campaigns. These cookies track visitors across websites and collect information to provide customized ads. Others Others Other uncategorized cookies are those that are being analyzed and have not been classified into a category as yet. SAVE & ACCEPT Powered by CookieYes Logo Go to Top

Từ khóa » Bó Xué