LC-MS (Xevo G2-XS) - Mass Spectrometry Research Facility

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MS Staff Member:

John Walsby-Tickle

Location:

Basement MS (00.097)

Booking:

Instrument Booking System

Training required:

Yes

Training prerequisites:

Previous experience or knowledge of LC-MS systems

Instrument description:

The Waters Xevo G2-XS is a bench-top QTOF mass spectrometer, designed for the analysis of a wide range of compounds in complex and challenging samples. The instrument incorporates StepWaveTM ion-transfer optics which increase the efficiency of ion transfer and remove neutral species from the ion beam, increasing sensitivity. The instrument is equiped with an ESI LockSprayTM source to allow accurante mass analysis by direct infusion or by LC. The XS collision cell allows fast and sensitive MS/MS experiments to be performed alongisde conventional experiments. The Acquity UPLC system allows seperation of complex mixtures for small molecule analysis, or desalting for protein analysis.

Typical applications:

High resolution LC-MS, Protein analysis, MS/MS experiments

Protocols

Software

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