Overview Of The Diverse Roles Of Bacterial And Archaeal ... - PubMed

Full text links CiteDisplay options Display options Format AbstractPubMedPMID

Abstract

As discovered over the past 25 years, the cytoskeletons of bacteria and archaea are complex systems of proteins whose central components are dynamic cytomotive filaments. They perform roles in cell division, DNA partitioning, cell shape determination and the organisation of intracellular components. The protofilament structures and polymerisation activities of various actin-like, tubulin-like and ESCRT-like proteins of prokaryotes closely resemble their eukaryotic counterparts but show greater diversity. Their activities are modulated by a wide range of accessory proteins but these do not include homologues of the motor proteins that supplement filament dynamics to aid eukaryotic cell motility. Numerous other filamentous proteins, some related to eukaryotic IF-proteins/lamins and dynamins etc, seem to perform structural roles similar to those in eukaryotes.

Keywords: Actin; Archaea; Bacterial cell division; Cell constriction; Cytomotive filaments; Dynamic instability; ESCRT; FtsZ; MreB; ParM; Plasmid segregation; Sliding filament motility; Treadmilling; TubZ; Tubulin.

PubMed Disclaimer

Similar articles

• Prokaryotic cytoskeletons: protein filaments organizing small cells. Wagstaff J, Löwe J. Wagstaff J, et al. Nat Rev Microbiol. 2018 Apr;16(4):187-201. doi: 10.1038/nrmicro.2017.153. Epub 2018 Jan 22. Nat Rev Microbiol. 2018. PMID: 29355854 Review.
• Prokaryotic cytoskeletons: in situ and ex situ structures and cellular locations. Kim KW. Kim KW. Antonie Van Leeuwenhoek. 2019 Feb;112(2):145-157. doi: 10.1007/s10482-018-1142-5. Epub 2018 Aug 20. Antonie Van Leeuwenhoek. 2019. PMID: 30128891 Review.
• Structure and Dynamics of Actin-Like Cytomotive Filaments in Plasmid Segregation. Gayathri P, Harne S. Gayathri P, et al. Subcell Biochem. 2017;84:299-321. doi: 10.1007/978-3-319-53047-5_10. Subcell Biochem. 2017. PMID: 28500530 Review.
• Structural/functional homology between the bacterial and eukaryotic cytoskeletons. Amos LA, van den Ent F, Löwe J. Amos LA, et al. Curr Opin Cell Biol. 2004 Feb;16(1):24-31. doi: 10.1016/j.ceb.2003.11.005. Curr Opin Cell Biol. 2004. PMID: 15037301 Review.
• Evolution of cytomotive filaments: the cytoskeleton from prokaryotes to eukaryotes. Löwe J, Amos LA. Löwe J, et al. Int J Biochem Cell Biol. 2009 Feb;41(2):323-9. doi: 10.1016/j.biocel.2008.08.010. Epub 2008 Aug 13. Int J Biochem Cell Biol. 2009. PMID: 18768164 Review.

See all similar articles

Cited by

• A unique cell division protein critical for the assembly of the bacterial divisome. Chu X, Wang L, Zhu Y, Feng Z, Guan Q, Song L, Luo Z. Chu X, et al. Elife. 2024 Oct 3;12:RP87922. doi: 10.7554/eLife.87922. Elife. 2024. PMID: 39361022 Free PMC article.
• Cell polarity: having and making sense of direction-on the evolutionary significance of the primary cilium/centrosome organ in Metazoa. Bornens M. Bornens M. Open Biol. 2018 Aug;8(8):180052. doi: 10.1098/rsob.180052. Open Biol. 2018. PMID: 30068565 Free PMC article. Review.
• Unique Properties of the Alpha-Helical DNA-Binding Protein KfrA Encoded by the IncU Incompatibility Group Plasmid RA3 and Its Host-Dependent Role in Plasmid Maintenance. Lewicka E, Mitura M, Steczkiewicz K, Kieracinska J, Skrzynska K, Adamczyk M, Jagura-Burdzy G. Lewicka E, et al. Appl Environ Microbiol. 2021 Jan 4;87(2):e01771-20. doi: 10.1128/AEM.01771-20. Print 2021 Jan 4. Appl Environ Microbiol. 2021. PMID: 33097508 Free PMC article.
• Towards the Idea of Molecular Brains. Timsit Y, Grégoire SP. Timsit Y, et al. Int J Mol Sci. 2021 Nov 1;22(21):11868. doi: 10.3390/ijms222111868. Int J Mol Sci. 2021. PMID: 34769300 Free PMC article. Review.
• Intracellular Organization by Jumbo Bacteriophages. Guan J, Bondy-Denomy J. Guan J, et al. J Bacteriol. 2020 Dec 18;203(2):e00362-20. doi: 10.1128/JB.00362-20. Print 2020 Dec 18. J Bacteriol. 2020. PMID: 32868402 Free PMC article. Review.

See all "Cited by" articles

Publication types

• Review Actions
  • Search in PubMed
  • Search in MeSH
  • Add to Search

MeSH terms

• Archaea / cytology* Actions
  • Search in PubMed
  • Search in MeSH
  • Add to Search
• Archaeal Proteins / metabolism Actions
  • Search in PubMed
  • Search in MeSH
  • Add to Search
• Bacteria / cytology* Actions
  • Search in PubMed
  • Search in MeSH
  • Add to Search
• Bacterial Proteins / metabolism Actions
  • Search in PubMed
  • Search in MeSH
  • Add to Search
• Cytoskeleton / metabolism* Actions
  • Search in PubMed
  • Search in MeSH
  • Add to Search

Substances

• Archaeal Proteins Actions
  • Search in PubMed
  • Search in MeSH
  • Add to Search
• Bacterial Proteins Actions
  • Search in PubMed
  • Search in MeSH
  • Add to Search

Grants and funding

• MC_U105184326/MRC_/Medical Research Council/United Kingdom

LinkOut - more resources

• Full Text Sources

  • Springer

• Other Literature Sources

  • scite Smart Citations

• Research Materials

  • NCI CPTC Antibody Characterization Program

• Miscellaneous

  • NCI CPTAC Assay Portal