Rabbit Anti Histone H1.3 - Bio-Rad Antibodies

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Histone H1.3 antibody ISO 9001 Quality Assurance Manufacturing | Print

Rabbit anti Histone H1.3

Product Type PrecisionAb Polyclonal Isotype Polyclonal IgG Format Purified Specificity Histone H1.3

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• Secondary Antibodies
• Applications
• Storage Information
• Batch/Lot Specific Datasheets

Antibody Quality and Performance Guarantee Unrivaled Technical Support 1 Formats Available: Purified

Product Code	Applications	Pack Size	List Price	Your Price	Qty
VPA00783 Datasheet SDS SDS WB 100 µl Log in - + Add to Cart Add to Quote Get Quote List Price Your Price Log in

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Product Description

Rabbit anti Human histone H1.3 antibody recognizes histone H1.3, also known as histone H1c, H1-3 and H1s-2. Histones are the major protein component of chromatin, with important roles in gene regulation. Histone H1 binds to linker DNA between nucleosomes, plays a role in higher-order chromatin stabilization, and is also able to fine-tune gene transcription in a locus-specific way (Brockers and Schneider, 2019). Histone variants replace canonical histones when nucleosomes are disrupted, with diverse implications for epigenetic gene regulation. Histone H1.3 is a histone variant and appears to have diverse roles in cancer. This protein has been suggested as a prognostic biomarker for pancreatic ductal adenocarcinoma (Bauden et al. 2017). Histone H1.3 has also been identified as a repressor for the oncogene H19, contributing to the suppression of epithelial ovarian carcinogenesis (Medrzycki et al. 2015).

Product Details

Target Species Human Western Blotting Anti histone H1.3 antibody recognizes a band of approximately 30 kDa in Jurkat cell lysates. Product Form Purified IgG - liquid Preparation Rabbit polyclonal antibody purified by affinity chromatography on immunogen. Buffer Solution Phosphate buffered saline. Preservative Stabilisers 0.09% Sodium Azide (NaN3)2% Sucrose Immunogen Synthetic peptide directed towards the N terminal region of human histone H1.3 Approx. Protein Concentrations IgG concentration 0.5 mg/ml. Regulatory For research purposes only. Guarantee 12 months from date of despatch. Acknowledgements PrecisionAb is a trademark of Bio-Rad Laboratories.

Storage Information

This product is shipped at ambient temperature.Store undiluted at -20°C, avoiding repeated freeze thaw cycles.

Applications

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.

Application Name	Verified	Min Dilution	Max Dilution
Western Blotting	1/1000

The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Learn about how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

Secondary Antibodies Available

Description	Product Code	Applications	Pack Size	List Price	Your Price	Quantity
Goat anti Rabbit IgG (H/L):HRP	STAR208P	E WB	2 ml		Log in	- +	Add to Cart Get Quote Add to Quote
List Price	Your Price
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Description	Goat anti Rabbit IgG (H/L):HRP

Bioinformatics

UniProt P16402 Entrez Gene HIST1H1D GO Terms GO:0000786 nucleosome GO:0003677 DNA binding GO:0006334 nucleosome assembly GO:0005634 nucleus

Batch/Lot Specific Datasheets

VPA00783

170515

If you cannot find the batch/lot you are looking for please contact our technical support team for assistance.

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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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