Vitamin B5: Everything You Need To Know

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Medical News TodaySubscribeWhat to know about vitamin B5

Medically reviewed by Ami Patel PharmD, BCPS — Written by Adam Felman — Updated on October 6, 2023

Function
Deficiency
Recommended intake
Food sources
Risks

Vitamin B5 is a water-soluble vitamin from the B group of vitamins. It helps produce energy by breaking down fats and carbohydrates. Its benefits include promoting healthy skin, hair, eyes, and liver.

People need B5 to synthesize and metabolize fats, proteins, and coenzyme A.

B5 is one of the less known vitamins, possibly because deficiencies of it are rare.

Vitamin B5 is also known as pantothenic acid, or Pantothenate. The word pantothenic comes from the Greek “pantou,” meaning everywhere. Nearly all foods contain small quantities of pantothenic acid.

Why do we need vitamin B5?

undersides of ripening mushrooms — Anthony-Masterson/Getty Images

Vitamin B5 has many important functions. These include:

converting food into glucose
synthesizing cholesterol
forming sex and stress-related hormones
forming red blood cells

As with all B vitamins, pantothenic acid helps the body break down fats, carbohydrates, and proteins so that our bodies can use them for energy and rebuilding tissues, muscles, and organs.

Coenzyme A

Vitamin B5 has a role in synthesizing coenzyme A.

Coenzyme A is involved in the synthesis of fatty acids and is important for converting foods into fatty acids and cholesterol.

Coenzyme A is also needed for the creation of sphingosine, a fat-like molecule that helps deliver chemical messages inside the body’s cells.

The liver needs Coenzyme A to metabolize some drugs and toxins safely.

Digestive system

Vitamin B5 helps maintain a healthy digestive system and assists the body in using other vitamins, especially vitamin B2. Vitamin B2 helps manage stress, but there is no evidence that pantothenic acid reduces stress.

Skin care

Some studies have shown that vitamin B5 works as a moisturizer on the skin and enhances the healing process of skin wounds.

One study showed that vitamin B5 helped facial acne and reduced the number of acne-related facial blemishes when taken as a dietary supplement. Researchers noted a “significant mean reduction in total lesion count” after 12 weeks of taking a B5 dietary supplement. The authors call for more trials to confirm the results.

Cholesterol and triglycerides

Some studies suggest that vitamin B5 intake can help lower cholesterol and levels of blood triglycerides, or fats. This course of management should only be pursued under medical supervision.

Rheumatoid arthritis

Some researchers have found that people with rheumatoid arthritis have lower levels of vitamin B5. However, more evidence is needed to confirm these results.

Deficiency

Vitamin B5 deficiency is extremely rare in people as pantothenic acid is found in nearly all foods. A healthy and varied diet should provide a person with enough. Because of this, vitamin B5 levels are not routinely tested for, like Vitamin B12 levels are.

A deficiency in vitamin B5 may lead to:

tiredness
apathy
irritability
sleep disorders
stomach pains
nausea
vomiting
numbness
muscle cramps
hypoglycemia
burning feet or hands (paresthesia)
restlessness
malaise

In mice, a vitamin B5 deficiency led to skin irritation and graying of the fur, but this was reversed when pantothenic acid was given.

However, according to Oregon State University, when the level of B5 intake is restored to normal, many of these symptoms are reversed.

Recommended daily intake

Daily intake can be obtained from food, a multivitamin, a b-complex vitamin or a pantothenic acid vitamin supplement. Experts recommend:

Infants 0-6 months – 1.7 milligrams (mg) per day
Infants 7-12 months – 1.8 mg per day
Children 1 -3 years – 2 mg per day
Children 4-8 years – 3 mg per day
Children 9-13 years – 4 mg per day
Males and females 14 years and over – 5 mg per day
Pregnant women – 6 mg per day
Breastfeeding women – 7 mg per day

Vitamin B5 is soluble in water and is excreted in urine. Our bodies do not store it, and we need to consume it every day to replenish supplies.

Food sources of Vitamin B5

Vitamin B5 is widely found in both animals and plant products.

Sources include:

Meat: Pork, chicken, turkey, duck, beef, and especially animal organs such as liver and kidney
Fish: Salmon, lobster, and shellfish.
Grains: Whole grain breads and cereals. Whole grains are a good source of vitamin B5 but milling can remove up to 75 percent of the B5 content.
Dairy products: Egg yolk, milk, yogurt, and milk products.
Legumes: Lentils, split peas, and soybeans.
Vegetables: Mushrooms, avocado, broccoli, sweet potatoes, corn, cauliflower, kale, and tomatoes.

Other sources of vitamin B5 include brewer’s yeast, peanuts, sunflower seeds, wheat germ, royal jelly, and oatmeal Pantothenic acid is widely available in food, but it is lost in processing, for example, in canning, freezing, and milling.

To ensure an adequate intake, foods should be eaten fresh rather than refined. As with all water-soluble vitamins, vitamin B5 is lost when food is boiled.

Scientists have found that bacteria in the lining of the colon might generate pantothenic acid, but this has not yet been proved.

Side effects and interactions

Pantothenic acid is taken as a supplement for a number of conditions, but there is not enough evidence to prove that it is effective in most of these cases.

For people who stay within the recommended daily dose of Vitamin B5, or slightly above, the use of a supplement is likely to be safe, but anyone who is considering taking a supplement should consult a doctor first.

A very high dose, for example, of 10-20 grams (gm) a day, may cause diarrhea. If vitamin B5 is taken as a supplement, it can cause an imbalance in other B vitamins. For this reason, it is preferable to take a B complex vitamin. This should be taken after eating, with water.

Royal jelly contains vitamin B5 so care should be taken not to consume royal jelly alongside a vitamin B5 supplement.

Vitamin B5 can interact with some drugs. It may interfere with the absorption and effectiveness of the antibiotic, azithromycin.

Women should not take more than 6 mg a day when pregnant, and 7 mg when breast-feeding, as it may not be safe.

It is always best to check with a doctor before taking a supplement, especially for people with an existing health condition and those who are taking other drugs.

Article resources

Hrubša M, et al. (2022). Biological properties of vitamins of the B-complex, part 1: Vitamins B1, B2, B3, and B5. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8839250/
Pantothenic acid. (2015). http://lpi.oregonstate.edu/mic/vitamins/pantothenic-acid
Pantothenic acid – Fact sheet for consumers. (2021). https://ods.od.nih.gov/factsheets/PantothenicAcid-Consumer/
Pantothenic acid – Fact sheet for professionals. (2021). https://ods.od.nih.gov/factsheets/PantothenicAcid-HealthProfessional/
Sanvictores T & Chauhan S. (2023). Vitamin B5 (Pantothenic acid). https://www.ncbi.nlm.nih.gov/books/NBK563233/
Tate W. (2014). Arthritis benefits of Vitamin B5 rich foods. https://arthritiscure.me/arthritis-benefits-of-vitamin-b5-richfoods/
Vitamin B5 – Pantothenic acid. (n.d.). https://med.libretexts.org/Courses/Dominican_University/DU_Bio_1550%3A_Nutrition_(LoPresto)/7%3A_Vitamins/7.3%3A_Water_Soluble_Vitamins/Vitamin_B5_(Pantothenic_acid)
Yang M, et al. (2014). A randomized, double-blind, placebo-controlled study of a novel pantothenic acid-based dietary supplement in subjects with mild to moderate facial acne. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4065280/

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Nutrition / Diet

How we reviewed this article:

SourcesMedical News Today has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical journals and associations. We only use quality, credible sources to ensure content accuracy and integrity. You can learn more about how we ensure our content is accurate and current by reading our editorial policy.

Hrubša M, et al. (2022). Biological properties of vitamins of the B-complex, part 1: Vitamins B1, B2, B3, and B5.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8839250/
Pantothenic acid: Fact sheet for consumers. (2021).https://ods.od.nih.gov/factsheets/PantothenicAcid-Consumer/
Pantothenic acid: Fact sheet for health professionals. (2021).https://ods.od.nih.gov/factsheets/PantothenicAcid-HealthProfessional/
Pantothenic acid. (2015).http://lpi.oregonstate.edu/mic/vitamins/pantothenic-acid
Sanvictores T, et al. (2023). Vitamin B5 (pantothenic acid).https://www.ncbi.nlm.nih.gov/books/NBK563233/
Tate W. (2014). Arthritis benefits of vitamin B5 richfoods.https://arthritiscure.me/arthritis-benefits-of-vitamin-b5-richfoods/
Vitamin B5 (pantothenic acid). (n.d.).https://med.libretexts.org/Courses/Dominican_University/DU_Bio_1550%3A_Nutrition_(LoPresto)/7%3A_Vitamins/7.3%3A_Water_Soluble_Vitamins/Vitamin_B5_(Pantothenic_acid)
Yang M, et al. (2014). A randomized, double-blind, placebo-controlled study of a novel pantothenic acid-based dietary supplement in subjects with mild to moderate facial acne.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4065280/

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Medically reviewed by Ami Patel PharmD, BCPS — Written by Adam Felman — Updated on October 6, 2023

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Why do we need vitamin B5?

Coenzyme A

Digestive system

Skin care

Cholesterol and triglycerides

Rheumatoid arthritis

Deficiency

Recommended daily intake

Food sources of Vitamin B5

Side effects and interactions

Article resources

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