5 Aug 2022 · This is an intronless gene that is involved in cholesterol and lipid metabolism. The encoded protein is a membrane protein and contains ...
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6 Jun 2022 · CH25H (Cholesterol 25-Hydroxylase) is a Protein Coding gene. Diseases associated with CH25H include Lysosomal Acid Lipase Deficiency and ...
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CH25H is an interferon-stimulated gene, and its primary product 25HC may have broad-spectrum antiviral activity, demonstrated in mice against HIV, ebola, ...
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Catalyzes the formation of 25-hydroxycholesterol from cholesterol, leading to repress cholesterol biosynthetic enzymes (PubMed:11967195, PubMed:11207193).
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25 Nov 2020 · CH25H encodes cholesterol 25-hydroxylase that catalyzes the formation of 25-hydroxycholesterol (25HC) from cholesterol (23). In many cell types, ...
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6 Feb 2019 · Ch25h−/− mice and RoraSg/+ mice (a spontaneous RORα mutant strain) were obtained from the Jackson Laboratory. Homozygous RoraSg/Sg mice ...
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CH25H catalyzes the formation of 25-hydroxycholesterol (25-HC) from cholesterol and contributes to the first steps in bile acid and oxysterol synthesis pathways ...
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Splice variant, UniProt, Protein class, Gene ontology, Length & mass, Signal peptide (predicted), Transmembrane regions (predicted). CH25H-201
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12 Dec 2019 · The membrane-associated enzyme cholesterol 25-hydroxylase (Ch25h) catalyzes the formation of 25-hydroxycholesterol (25HC, oxysterol) from ...
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7 Feb 2019 · Cholesterol 25-hydroxylase (CH25H) is an interferon (IFN)-induced gene that catalyzes the oxidation of cholesterol to 25-hydroxycholesterol ...
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View mouse Ch25h Chr19:34451183-34452548 with: phenotypes, sequences, polymorphisms, proteins, references, function, expression.
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Homozygous Ch25h (cholesterol 25-hydroxylase) knock-out mice have increased levels of IgA and may be useful in studies innate and adaptive immune system ...
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6 Jul 2020 · Cholesterol-25-hydroxylase (CH25H) and its enzymatic products 25-hydroxycholesterol (25HC), a well-known oxysterol that regulates lipid ...
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KEGG Orthology (KO) [BR:ko00001] 09100 Metabolism 09103 Lipid metabolism 00120 Primary bile acid biosynthesis. K10223 CH25H; cholesterol 25-hydroxylase
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