GX-936 | CAS#:1235406-09-3 | Chemsrc

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GX-936 Modify Date: 2025-09-14 14:25:40

GX-936 structure	Common Name	GX-936
	CAS Number	1235406-09-3	Molecular Weight	575.585
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C24H20F3N7O3S2	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of GX-936 GX-936 (PF 05196233) is a potent Nav1.7 inhibitor that binds to the activated state of voltage-sensor domain IV (VSD4), exhibits robust inhibition of the 1KαPMTX-evoked N1742K response with IC50 of 40 nM; inhibits Nav1.7 through a voltage-sensor trapping mechanism, likely by stabilizing inactivated states of the channel.

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Names

Name	GX-936

GX-936 Biological Activity

Description	GX-936 (PF 05196233) is a potent Nav1.7 inhibitor that binds to the activated state of voltage-sensor domain IV (VSD4), exhibits robust inhibition of the 1KαPMTX-evoked N1742K response with IC50 of 40 nM; inhibits Nav1.7 through a voltage-sensor trapping mechanism, likely by stabilizing inactivated states of the channel.
References	References 1. Ahuja S, et al. Science. 2015 Dec 18;350(6267):aac5464. 2. Chernov-Rogan T, et al. Proc Natl Acad Sci U S A. 2018 Jan 23;115(4):E792-E801. View Related Products by Target Sodium Channel

Chemical & Physical Properties

Molecular Formula	C24H20F3N7O3S2
Molecular Weight	575.585
InChIKey	UCAVSLIXTXZSRD-UHFFFAOYSA-N
SMILES	CCN1CC(n2nccc2-c2cc(C(F)(F)F)ccc2Oc2ccc(S(=O)(=O)Nc3ncns3)cc2C#N)C1

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact [email protected].

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• Shanghai Nianxing Industrial Co., Ltd
• China
• Product Name: GX-936
• Price: Check
• Purity: 98.0%
• Delivery: 10 Day
• Contact: Yang
• Email: [email protected]

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Chemsrc provides GX-936(CAS#:1235406-09-3) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of GX-936 are included as well.>> amp version: GX-936 ×

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